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A Powerful Predictor of Outcome in Mantle Cell Lymphoma
Status of measurable residual disease during induction, consolidation, and maintenance therapy strongly correlated with subsequent risk for disease progression.
Pancreatic Cancer Screening of High-Risk Individuals Leads to Early-Stage Diagnosis
Most high-risk patients diagnosed during surveillance had resectable, stage I disease and could achieve long-term survival.
Is Recurrence-Free Survival an Adequate Endpoint in Studies of Colorectal Liver Metastasis?
Minimal correlation was found between RFS and overall survival in patients who underwent curative hepatic resection.
Luspatercept for Non–Transfusion-Dependent β-Thalassemia
Luspatercept increased hemoglobin concentrations by at least 1g/dL compared with placebo.
Colonoscopy Screening for Colorectal Cancer: A Randomized Trial
Screening didn't lower mortality in a primary analysis, but that's not the end of the story.
Reassessing Safety of Vaginal Estrogen in Women with Breast Cancer
Use of vaginal estrogen therapy or menopausal hormone therapy was not associated with increased risk for either recurrence or mortality.
Cisplatin plus Irinotecan or Etoposide for Neuroendocrine Cancers of the GI Tract?
Survival outcomes were similar with the two regimens.
A New Destination for Myeloma CAR T-Cell Therapy
Targeting GPRC5D provided a high response rate in patients with relapsed or refractory myeloma, including those with relapses after anti-BCMA-directed immunotherapies.
Does COVID-19 Confer Risk for Venous Thromboembolism in Ambulatory Patients?
A U.K. study suggests that it does, particularly in unvaccinated patients.