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Segmentectomy Is Supported as Standard of Care for Small, Peripheral Non–Small-Cell Lung Cancer
In a randomized trial, segmentectomy was noninferior to lobectomy in terms of overall survival.
More Support for Nivolumab plus Chemotherapy in Gastric Cancer
The addition of nivolumab was associated with improvement in progression-free survival but not overall survival in this placebo-controlled trial.
Mitapivat for the Treatment of Pyruvate Kinase Deficiency
An activator of red cell pyruvate kinase improved hemoglobin and quality of life in patients with PK deficiency.
Medicaid, the ACA, and Breast Cancer Survival
Survival improved for patients with metastatic breast cancer in states that expanded Medicaid coverage, and the disparity between white and other racial/ethnic groups decreased.
Excess Risk for Venous Thromboembolism Persists for Months After COVID-19
But risks are less elevated for those who do not require hospitalization.
Ipilimumab/Nivolumab Not Superior to Chemotherapy in Gastric Cancer
Outcomes were not better with ipilimumab plus nivolumab in patients with CPS >5% and in all randomized patients.
Improving Survival in Patients with De Novo Metastatic Prostate Cancer
The addition of abiraterone to ADT plus docetaxel was associated with increased overall and radiographic progression-free survival.
Trends in Lung Cancer Presentation and Survival in the Era of Screening
Early-stage diagnoses and all-cause survival accelerated in 2014, after CT screening was recommended for high-risk patients.
Progress in Targeted Therapy for Acute Myeloid Leukemia
The addition of ivosidenib to azacitidine improved outcomes and survival in patients with IDH1-mutated AML.